A trial with IgY chicken antibodies to eradicate faecal carriage of Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases

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Jonsson, Anna-Karin ; Larsson, Anders ; Tängdén, Thomas ; Melhus, Åsa ; Lannergård, Anders (2015)
  • Publisher: Co-Action Publishing
  • Journal: Infection Ecology & Epidemiology, volume 5 (issn: 2000-8686, eissn: 2000-8686)
  • Related identifiers: pmc: PMC4641892, doi: 10.3402/iee.v5.28224, doi: 10.3402/iee.v%v.28224
  • Subject: Escherichia coli | extended spectrum beta-lactamase | faecal carriage | infectious control | stool colonisation | CTX-M-15 | RC109-216 | avian antibody | clonal outbreak | immunotherapy | Enterobacteriaceae | Infectious and parasitic diseases | Original Research Article | Clonal outbreak; Enterobacteriaceae; Klebsiella pneumoniae; Escherichia coli; CTX-M-15; IgY chicken antibody; avian antibody; immunotherapy; infectious control; extended-spectrum beta-lactamase; faecal carriage | Klebsiella pneumoniae | IgY chicken antibody

Background: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden, an orphan drug tri... View more
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