A randomised comparative study of the short term clinical and biological effects of intravenous pulse methylprednisolone and infliximab in patients with active rheumatoid arthritis despite methotrexate treatment.
Subject: Antibodies, Monoclonal | Extended Report | C-Reactive Protein | Aged | Methylprednisolone | Methotrexate | Middle Aged | Matrix Metalloproteinase 3 | Interleukin-6 | Immunosuppressive Agents | Arthritis, Rheumatoid | Severity of Illness Index | Antirheumatic Agents | Drug Therapy, Combination | Glucocorticoids | Adult | Female | Quality of Life | Single-Blind Method | Humans | Male
OBJECTIVES: To compare the short term clinical and biological effects of intravenous (i.v.) pulse methylprednisolone (MP) and infliximab (IFX) in patients with severe active rheumatoid arthritis (RA) despite methotrexate (MTX) treatment. METHODS: Patients with active RA... View more