Ion Channel Profile of TRPM8 Cold Receptors Reveals a Role of TASK-3 Potassium Channels in Thermosensation

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Cruz Morenilla-Palao; Enoch Luis; Carlos Fernández-Peña; Eva Quintero; Janelle L. Weaver; Douglas A. Bayliss; Félix Viana;

Animals sense cold ambient temperatures through the activation of peripheral thermoreceptors that express TRPM8, a cold- and menthol-activated ion channel. These receptors can discriminate a very wide range of temperatures from innocuous to noxious. The molecular mechan... View more
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