A Mitochondrial Power Play in Lymphoma
Article, Other literature type
DeBerardinis, Ralph J.
- Publisher: Elsevier BV
Cell Biology | Article | Cancer Research | Oncology
Deregulated energetics is a hallmark of malignancy, but metabolic heterogeneity among individual tumors is unknown. A study by Caro et al. in this issue of Cancer Cell demonstrates that a subset of lymphomas is defined by reliance on mitochondrial energy generation and is selectively killed when this pathway is impaired.