Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5’UTR and PI3K Signaling

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Zhuo Min; Ying Tang; Xiao-Tong Hu; Bing-Lin Zhu; Yuan-Lin Ma; Jing-Si Zha; Xiao-Juan Deng; Zhen Yan; Guo-Jun Chen;
(2018)

The α-secretase “a disintegrin and metalloproteinase domain-containing protein” (ADAM10) is involved in the processing of amyloid precursor protein (APP). Upregulation of ADAM10 precludes the generation of neurotoxic β-amyloid protein (Aβ) and represents a plausible the... View more
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