Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA.

Article English OPEN
Suits, Michael D.; Boraston, Alisdair B.;
(2013)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 8,issue 7 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0067190, pmc: PMC3718772
  • Subject: Computational Biology | Research Article | Biology | Materials Science | Infectious Diseases | Microbiology | Medicine | Bacterial Pathogens | Streptococci | Protein Structure | Bacterial Diseases | Q | Crystallography | R | Proteins | Biochemistry | Science | Streptococcal Infections | Macromolecular Structure Analysis

PfbA (plasmin- and fibronectin-binding protein A) is an extracellular Streptococcus pneumoniae cell-wall attached surface protein that binds to fibronectin, plasmin, and plasminogen. Here we present a structural analysis of the surface exposed domains of PfbA using a co... View more
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