Interaction of rocuronium with human liver cytochromes P450

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Eva Anzenbacherova; Alena Spicakova; Lenka Jourova; Jitka Ulrichova; Milan Adamus; Petr Bachleda; Pavel Anzenbacher;

Rocuronium is a neuromuscular blocking agent acting as a competitive antagonist of acetylcholine. Results of an inhibition of eight individual liver microsomal cytochromes P450 (CYP) are presented. As the patients are routinely premedicated with diazepam, possible inter... View more
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