Interethnic diversity of the CD209 (rs4804803) gene promoter polymorphism in African but not American sickle cell disease

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Noble, Jenelle A.; Duru, Kimberley C.; Guindo, Aldiouma; Yi, Li; Imumorin, Ikhide G.; Diallo, Dapa A.; Thomas, Bolaji N.;
(2015)
  • Publisher: PeerJ Inc.
  • Journal: PeerJ,volume 3 (eissn: 2167-8359)
  • Related identifiers: pmc: PMC4349147, doi: 10.7717/peerj.799
  • Subject: Molecular Biology | Africa | Interethnic | Caucasians | Evolutionary Studies | Sickle cell disease | Hematology | Diversity | Genetics | Co-morbidities | CD209 | Populations | African Americans

Elucidating the genomic diversity of CD209 gene promoter polymorphism could assist in clarifying disease pathophysiology as well as contribution to co-morbidities. CD209 gene promoter polymorphism has been shown to be associated with susceptibility to infection. We hypo... View more
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