TGF-β1 autocrine signalling and enamel matrix components

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Kobayashi-Kinoshita, Saeko; Yamakoshi, Yasuo; Onuma, Kazuo; Yamamoto, Ryuji; Asada, Yoshinobu;
(2016)

Transforming growth factor-β1 (TGF-β1) is present in porcine enamel extracts and is critical for proper mineralization of tooth enamel. Here, we show that the mRNA of latent TGF-β1 is expressed throughout amelogenesis. Latent TGF-β1 is activated by matrix metalloprotein... View more
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