Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA

Article, Other literature type English OPEN
Gantz, Stephanie C.; Levitt, Erica S.; Llamosas, Nerea; Neve, Kim A.; Williams, John T.;
  • Publisher: Elsevier BV
  • Journal: Cell Reports,volume 12,issue 6,pages944-954 (issn: 2211-1247)
  • Related identifiers: doi: 10.1016/j.celrep.2015.07.005, pmc: PMC4536104
  • Subject: release | rat substantia-nigra | neurons | Article | QH301-705.5 | dorsal raphe nucleus | induced dyskinesia | receptor | in-vitro | BIOCHEMISTRY AND MOLECULAR BIOLOGY | amino-acid | parinsons-disease | Biology (General) | cerbrospinal-fluid

Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson's disease (PD) and psychiatric disorders. L-DOPA, the leading treatment of PD, facilitates the production and release of dopamine. This study... View more
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