publication . Article . Other literature type . Conference object . 2018

Matched Short-Term Depression and Recovery Encodes Interspike Interval at a Central Synapse.

Jeremy E. Niven; Sergio Rossoni; Sergio Rossoni; Armando E. Castillo;
Open Access English
  • Published: 11 Sep 2018 Journal: Scientific Reports (issn: 2045-2322, Copyright policy)
  • Publisher: Nature Publishing Group
  • Country: United Kingdom
Abstract
Abstract Reversible decreases in synaptic strength, known as short-term depression (STD), are widespread in neural circuits. Various computational roles have been attributed to STD but these tend to focus upon the initial depression rather than the subsequent recovery. We studied the role of STD and recovery at an excitatory synapse between the fast extensor tibiae (FETi) and flexor tibiae (flexor) motor neurons in the desert locust (Schistocerca gregaria) by making paired intracellular recordings in vivo. Over behaviorally relevant pre-synaptic spike frequencies, we found that this synapse undergoes matched frequency-dependent STD and recovery; higher frequency...
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doi: 10.1038/s41598-018-31996-0
pmid: 30206296
pmc: PMC6134063
Subjects
free text keywords: Medicine, R, Science, Q, Multidisciplinary, Article, Epsp amplitude, FETI, Schistocerca, biology.organism_classification, biology, Neuroscience, Excitatory postsynaptic potential, Chemistry, Biological neural network, Excitatory synapse, Synapse, Time constant
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RCUK| Visual navigation in ants: from visual ecology to brain
Project
Visual navigation in ants: from visual ecology to brain
  • Funder: Research Council UK (RCUK)
  • Project Code: BB/R005036/1
  • Funding stream: BBSRC
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