Upregulation of Ih expressed in IB4-negative Aδ nociceptive DRG neurons contributes to mechanical hypersensitivity associated with cervical radiculopathic pain

Article English OPEN
Liu, Da-Lu ; Lu, Na ; Han, Wen-Juan ; Chen, Rong-Gui ; Cong, Rui ; Xie, Rou-Gang ; Zhang, Yu-Fei ; Kong, Wei-Wei ; Hu, San-Jue ; Luo, Ceng (2015)
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports, volume 5 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: doi: 10.1038/srep16713, pmc: PMC4649360
  • Subject: Article
    mesheuropmc: nervous system

Cervical radiculopathy represents aberrant mechanical hypersensitivity. Primary sensory neuron’s ability to sense mechanical force forms mechanotransduction. However, whether this property undergoes activity-dependent plastic changes and underlies mechanical hypersensit... View more
Share - Bookmark