Role of Pleiotropy in the Evolution of a Cryptic Developmental Variation in Caenorhabditis elegans

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Duveau, Fabien; Félix, Marie-Anne;
(2012)
  • Publisher: Public Library of Science
  • Journal: PLoS Biology,volume 10,issue 1 (issn: 1544-9173, eissn: 1545-7885)
  • Related identifiers: doi: 10.1371/journal.pbio.1001230, pmc: PMC3250502
  • Subject: Evolutionary Selection | Quantitative Traits | Animal Models | Research Article | [ SDV.BDD ] Life Sciences [q-bio]/Development Biology | Evolutionary Processes | RILs | Recombinant Inbred Lines | Evolutionary Genetics | Evolutionary Biology | Genetics | GxE | GxG | quantitative trait locus | Population Genetics | near-isogenic lines | Biology | Epistasis | Developmental Biology | QTL | GLM | Complex Traits | Caenorhabditis Elegans | Heredity | generalized linear model | NILs | Model Organisms | genotype-by-environment | genotype-by-genotype | Animal Genetics | Evolutionary Developmental Biology | Cell Fate Determination | Genetic Polymorphism | Trait Locus

International audience; Robust biological systems are expected to accumulate cryptic genetic variation that does not affect the system output in standard conditions yet may play an evolutionary role once phenotypically expressed under a strong perturbation. Genetic vari... View more
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