Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro

Article, Other literature type English OPEN
Cherif, Hosni; Bisson, Daniel G.; Jarzem, Peter; Weber, Michael; Ouellet, Jean A.; Haglund, Lisbet;
(2019)

Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. Cells from degenerate and non-mildly-degenerate human IVD were obtained from organ dono... View more
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