Pharmacokinetics of neutron-irradiated meglumine antimoniate in Leishmania amazonensis-infected BALB/c mice

Collection, Article English OPEN
Borborema, Samanta Etel Treiger; Osso Junior, João Alberto; Andrade Junior, Heitor Franco de; Nascimento, Nanci do; (2019)
  • Publisher: Centro de Estudos de Venenos e Animais Peçonhentos
  • Related identifiers: doi: 10.6084/m9.figshare.7835348.v1
  • Subject: Toxicology | biodistribution | antimony | meglumine antimoniate | pharmacokinetics | Medicine | cutaneous leishmaniasis | radioisotope

<div><p>Abstract Background: Cutaneous leishmaniasis (CL) is a parasitic disease caused by the protozoan Leishmania spp. Pentavalent antimonial agents have been used as an effective therapy, despite their side effects and resistant cases. Their pharmacokinetics remain... View more
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