A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

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Hill, Emmeline W. ; Gu, Jingjing ; Eivers, Suzanne S. ; Fonseca, Rita G. ; McGivney, Beatrice A. ; Govindarajan, Preethi ; Orr, Nick ; Katz, Lisa M. ; MacHugh, David (2010)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 5, issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0008645, pmc: PMC2808334
  • Subject: Q | Genetics and Genomics/Animal Genetics | R | Research Article | Genetics and Genomics/Genomics | Science | Medicine | Genetics and Genomics/Population Genetics

Variants of the MSTN gene encoding myostatin are associated with muscle hypertrophy phenotypes in a range of mammalian species, most notably cattle, dogs, mice, and humans. Using a sample of registered Thoroughbred horses (n = 148), we have identified a novel MSTN seque... View more
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