Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case

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Zhang, Yunpeng; Liu, Wei; Xu, Yanjun; Li, Chunquan; Wang, Yingying; Yang, Haixiu; Zhang, Chunlong; Su, Fei; Li, Yixue; Li, Xia;
  • Publisher: Hindawi Publishing Corporation
  • Journal: BioMed Research International,volume 2,015 (issn: 2314-6133, eissn: 2314-6141)
  • Related identifiers: pmc: PMC4385567, doi: 10.1155/2015/501262
  • Subject: R | Research Article | Medicine | Article Subject

Identification of miRNA-mRNA modules is an important step to elucidate their combinatorial effect on the pathogenesis and mechanisms underlying complex diseases. Current identification methods primarily are based upon miRNA-target information and matched miRNA and mRNA ... View more
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