publication . Article . 2016

Sex Differences in Insular Cortex Gyri Responses to the Valsalva Maneuver

Macey, PM; Rieken, NS; Kumar, R; Ogren, JA; Middlekauff, HR; Wu, P; Woo, MA; Harper, RM;
Open Access English
  • Published: 01 Jun 2016 Journal: Frontiers in Neurology, volume 7 (issn: 1664-2295, eissn: 1664-2295, Copyright policy)
  • Publisher: Frontiers Media S.A.
Abstract
© 2016 Macey, Rieken, Kumar, Ogren, Middlekauff, Wu, Woo and Harper. Sex differences in autonomic regulation may underlie cardiovascular disease variations between females and males. One key autonomic brain region is the insular cortex, which typically consists of five main gyri in each hemisphere, and shows a topographical organization of autonomic function across those gyri. The present study aims to identify possible sex differences in organization of autonomic function in the insula. We studied brain functional magnetic resonance imaging (fMRI) responses to a series of four 18-s Valsalva maneuvers in 22 healthy females (age ± SD: 50.0 ± 7.9 years) and 36 hea...
Subjects
mesheuropmc: nervous system
free text keywords: autonomic, functional neuroanatomy, sympathetic, Neuroscience, Original Research, cardiovascular, fMRI
133 references, page 1 of 9

1 Ndayisaba JP Fanciulli A Granata R Duerr S Hintringer F Goebel G Sex and age effects on cardiovascular autonomic function in healthy adults. Clin Auton Res (2015) 25:317–26.10.1007/s10286-015-0310-1 26285905 [PubMed] [DOI]

2 Merz AA Cheng S Sex differences in cardiovascular ageing. Heart (2016) 102(11):825–31.10.1136/heartjnl-2015-308769 26917537 [OpenAIRE] [PubMed] [DOI]

3 Boynton RE Todd RL Blood pressure readings of 75,258 university students. Arch Intern Med (Chic) (1947) 80:454–62.10.1001/archinte.1947.00220160033003 20269267 [PubMed] [DOI]

4 Stamler J Stamler R Riedlinger WF Algera G Roberts RH. Hypertension screening of 1 million Americans. Community hypertension evaluation clinic (CHEC) program, 1973 through 1975. JAMA (1976) 235:2299–306.10.1001/jama.1976.03260470017018 946622 [PubMed] [DOI]

5 Narkiewicz K Phillips BG Kato M Hering D Bieniaszewski L Somers VK. Gender-selective interaction between aging, blood pressure, and sympathetic nerve activity. Hypertension (2005) 45:522–5.10.1161/01.HYP.0000160318.46725.46 15767469 [PubMed] [DOI]

6 Greenland P Reicher-Reiss H Goldbourt U Behar S. In-hospital and 1-year mortality in 1,524 women after myocardial infarction. Comparison with 4,315 men. Circulation (1991) 83:484–91.10.1161/01.CIR.83.2.484 1991367 [PubMed] [DOI]

7 Tunstall-Pedoe H Kuulasmaa K Amouyel P Arveiler D Rajakangas AM Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four conti nents. Circulation (1994) 90:583–612.10.1161/01.CIR.90.1.583 8026046 [PubMed] [DOI]

8 Ng AV Callister R Johnson DG Seals DR Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension (1993) 21:498–503.10.1161/01.HYP.21.4.498 8458648 [PubMed] [DOI]

9 Matsukawa T Sugiyama Y Watanabe T Kobayashi F Mano T Gender difference in age-related changes in muscle sympathetic nerve activity in healthy subjects. Am J Physiol (1998) 275:R1600–4.9791079 [PubMed]

10 Liao D Barnes RW Chambless LE Simpson RJ Jr Sorlie P Heiss G Age, race, and sex differences in autonomic cardiac function measured by spectral analysis of heart rate variability – the ARIC study. Atherosclerosis risk in communities. Am J Cardiol (1995) 76:906–12.10.1016/S0002-9149(99)80260-4 7484830 [PubMed] [DOI]

11 Del Rio G Verlardo A Zizzo G Marrama P Della Casa L Sex differences in catecholamine response to clonidine. Int J Obes Relat Metab Disord (1993) 17:465–9.8401749 [PubMed]

12 Abdel-Rahman AR Merrill RH Wooles WR Gender-related differences in the baroreceptor reflex control of heart rate in normotensive humans. J Appl Physiol (1985) (1994) 77:606–13.8002506 [PubMed]

13 Dart AM Du XJ Kingwell BA Gender, sex hormones and autonomic nervous control of the cardiovascular system. Cardiovasc Res (2002) 53:678–87.10.1016/S0008-6363(01)00508-9 11861039 [PubMed] [DOI]

14 Hinojosa-Laborde C Chapa I Lange D Haywood JR Gender differences in sympathetic nervous system regulation. Clin Exp Pharmacol Physiol (1999) 26:122–6.10.1046/j.1440-1681.1999.02995.x 10065332 [PubMed] [DOI]

15 Cosgrove KP Mazure CM Staley JK. Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol Psychiatry (2007) 62:847–55.10.1016/j.biopsych.2007.03.001 17544382 [OpenAIRE] [PubMed] [DOI]

133 references, page 1 of 9
Abstract
© 2016 Macey, Rieken, Kumar, Ogren, Middlekauff, Wu, Woo and Harper. Sex differences in autonomic regulation may underlie cardiovascular disease variations between females and males. One key autonomic brain region is the insular cortex, which typically consists of five main gyri in each hemisphere, and shows a topographical organization of autonomic function across those gyri. The present study aims to identify possible sex differences in organization of autonomic function in the insula. We studied brain functional magnetic resonance imaging (fMRI) responses to a series of four 18-s Valsalva maneuvers in 22 healthy females (age ± SD: 50.0 ± 7.9 years) and 36 hea...
Subjects
mesheuropmc: nervous system
free text keywords: autonomic, functional neuroanatomy, sympathetic, Neuroscience, Original Research, cardiovascular, fMRI
133 references, page 1 of 9

1 Ndayisaba JP Fanciulli A Granata R Duerr S Hintringer F Goebel G Sex and age effects on cardiovascular autonomic function in healthy adults. Clin Auton Res (2015) 25:317–26.10.1007/s10286-015-0310-1 26285905 [PubMed] [DOI]

2 Merz AA Cheng S Sex differences in cardiovascular ageing. Heart (2016) 102(11):825–31.10.1136/heartjnl-2015-308769 26917537 [OpenAIRE] [PubMed] [DOI]

3 Boynton RE Todd RL Blood pressure readings of 75,258 university students. Arch Intern Med (Chic) (1947) 80:454–62.10.1001/archinte.1947.00220160033003 20269267 [PubMed] [DOI]

4 Stamler J Stamler R Riedlinger WF Algera G Roberts RH. Hypertension screening of 1 million Americans. Community hypertension evaluation clinic (CHEC) program, 1973 through 1975. JAMA (1976) 235:2299–306.10.1001/jama.1976.03260470017018 946622 [PubMed] [DOI]

5 Narkiewicz K Phillips BG Kato M Hering D Bieniaszewski L Somers VK. Gender-selective interaction between aging, blood pressure, and sympathetic nerve activity. Hypertension (2005) 45:522–5.10.1161/01.HYP.0000160318.46725.46 15767469 [PubMed] [DOI]

6 Greenland P Reicher-Reiss H Goldbourt U Behar S. In-hospital and 1-year mortality in 1,524 women after myocardial infarction. Comparison with 4,315 men. Circulation (1991) 83:484–91.10.1161/01.CIR.83.2.484 1991367 [PubMed] [DOI]

7 Tunstall-Pedoe H Kuulasmaa K Amouyel P Arveiler D Rajakangas AM Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four conti nents. Circulation (1994) 90:583–612.10.1161/01.CIR.90.1.583 8026046 [PubMed] [DOI]

8 Ng AV Callister R Johnson DG Seals DR Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension (1993) 21:498–503.10.1161/01.HYP.21.4.498 8458648 [PubMed] [DOI]

9 Matsukawa T Sugiyama Y Watanabe T Kobayashi F Mano T Gender difference in age-related changes in muscle sympathetic nerve activity in healthy subjects. Am J Physiol (1998) 275:R1600–4.9791079 [PubMed]

10 Liao D Barnes RW Chambless LE Simpson RJ Jr Sorlie P Heiss G Age, race, and sex differences in autonomic cardiac function measured by spectral analysis of heart rate variability – the ARIC study. Atherosclerosis risk in communities. Am J Cardiol (1995) 76:906–12.10.1016/S0002-9149(99)80260-4 7484830 [PubMed] [DOI]

11 Del Rio G Verlardo A Zizzo G Marrama P Della Casa L Sex differences in catecholamine response to clonidine. Int J Obes Relat Metab Disord (1993) 17:465–9.8401749 [PubMed]

12 Abdel-Rahman AR Merrill RH Wooles WR Gender-related differences in the baroreceptor reflex control of heart rate in normotensive humans. J Appl Physiol (1985) (1994) 77:606–13.8002506 [PubMed]

13 Dart AM Du XJ Kingwell BA Gender, sex hormones and autonomic nervous control of the cardiovascular system. Cardiovasc Res (2002) 53:678–87.10.1016/S0008-6363(01)00508-9 11861039 [PubMed] [DOI]

14 Hinojosa-Laborde C Chapa I Lange D Haywood JR Gender differences in sympathetic nervous system regulation. Clin Exp Pharmacol Physiol (1999) 26:122–6.10.1046/j.1440-1681.1999.02995.x 10065332 [PubMed] [DOI]

15 Cosgrove KP Mazure CM Staley JK. Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol Psychiatry (2007) 62:847–55.10.1016/j.biopsych.2007.03.001 17544382 [OpenAIRE] [PubMed] [DOI]

133 references, page 1 of 9
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Article . 2016

Sex Differences in Insular Cortex Gyri Responses to the Valsalva Maneuver

Macey, PM; Rieken, NS; Kumar, R; Ogren, JA; Middlekauff, HR; Wu, P; Woo, MA; Harper, RM;