Subject: Diphosphonates | Osteotomy | Osteotomia | Metabolismo | RD1-811 | Metabolism | Osso e ossos | Bone and bones | Difosfonatos | Surgery
PURPOSE: To check the effect of zoledronate in bone remodeling during bone healing. METHODS: Thirty rabbits were divided into two groups of fifteen animals each (control and experimental group respectively). Shaft osteotomy was performed on the cranial portion of the fi... View more
1. Fleisch H. New bisphosphonates in osteoporosis. Osteoporosis Int. 1993;3:15-22.
2. Russell RG, Rogers MJ, Frith JC, Luckman SP, Coxon FP, Benford HL, Croucher PI, Shipman C, Fleisch HA. The pharmacology of bisphosphonates and new insights into their mechanism of action. J Bone Miner Res.1999;14S:73S-9S.
3. Plotkin H, Rauch F, Bishop NJ, Montpetit K, Ruck-Gibis J, Travers R, Glorieux FH. pamidronato treatment of severe osteogenesis imperfecta in children under 3 years of age. J Clin Endocrinol Metabol. 2000;85:1846-50.
4. Sato M, Grasser W. Effects of biphosphonates on isolated rat osteclasts as examined light microscopy. J Bone Miner Res.1990;5:31-40.
5. Chappard D, Petitjean M, Alexandre C, Vico L, Minaire P, Riffat G. Cortical osteoclasts are less sensitive to etidronato than trabecular osteoclasts. J Bone Miner Res. 1991;6:673-80.
6. Little DG, Smith NC, Williams PR, Briody JN, Bilston LE, Smith EJ, Gardiner EM, Cowell CT. Zoledronic acid prevents ostopenia and increases bone strength in a rabbit model of distracion osteogenesis. J Bone Miner Res. 2003;18:1300-7.
7. Madsen JE, Berg-Larsen T, Kirkeby OJ, Falch JA, Nordsletten L. No adverse effects of clodronate on fracyure healing in rats. Acta Orthop Scand. 1998;69:532-6.
8. Li J, Mori S, Kaji Y, Kawanishi J, Akiyama T, Norimatsu H. Concentration of bisphosphonate (incadronate) in callus area and its effects on fracture healing in rats. J Bone Miner Res. 2000;15:2240-51.
9. Eyres KS, Bell MJ, Kanis JA. New bone formation during leg lengthening. Evaluated by dual energy X-ray absorptiometry. J Bone Joint Surg Br. 1993;75:96-106.
10. Matos MA, Gonçalves RR, Araújo FP. Modelo experimental de osteotomia em coelhos imaturos. Acta Ortop Bras. 2001;9:21-6.