The International Society for Extracellular Vesicles launches the first massive open online course on extracellular vesicles

Article English OPEN
Lässer, Cecilia ; Théry, Clotilde ; Buzás, Edit I. ; Mathivanan, Suresh ; Zhao, Weian ; Gho, Yong Song ; Lötvall, Jan (2016)
  • Publisher: Co-Action Publishing
  • Journal: Journal of Extracellular Vesicles, volume 5 (issn: 2001-3078, eissn: 2001-3078)
  • Related identifiers: doi: 10.3402/jev.v5.34299, pmc: PMC5165052
  • Subject: International Society for Extracellular Vesicles | Editorial | Coursera | Cytology | extracellular vesicles | education | exosomes | Exosomes; Microvesicles; Extracellular Vesicles; Education; Massive Open Online Course; MOOC; ISEV; International Society for Extracellular Vesicles; Coursera | massive open online course | QH573-671 | microvesicles

The International Society for Extracellular Vesicles (ISEV) has organised its first educational online course for students and beginners in the field of extracellular vesicles (EVs). This course, “Basics of Extracellular Vesicles,” uses recorded lectures from experts in the field and will be open for an unlimited number of participants. The course is divided into 5 modules and can be accessed at The first module is an introduction to the field covering the nomenclature and history of EVs. Module 2 focuses on the biogenesis and uptake mechanisms of EVs, as well as their RNA, protein and lipid cargo. Module 3 covers the collection and processing of cell culture media and body fluids such as blood, breast milk, cerebrospinal fluid and urine prior to isolation of EVs. Modules 4 and 5 present different isolation methods and characterisation techniques utilised in the EV field. Here, differential ultracentrifugation, size-exclusion chromatography, density gradient centrifugation, kit-based precipitation, electron microscopy, cryo-electron microscopy, flow cytometry, atomic-force microscopy and nanoparticle-tracking analysis are covered. This first massive open online course (MOOC) on EVs was launched on 15 August 2016 at the platform “Coursera” and is free of charge.Keywords: exosomes; microvesicles; extracellular vesicles; education; massive open online course; International Society for Extracellular Vesicles; Coursera(Published: 16 December 2016)Citation: Journal of Extracellular Vesicles 2016, 5: 34299 -
  • References (13)
    13 references, page 1 of 2

    1. Chargaff E, West R. The biological significance of the thromboplastic protein of blood. J Biol Chem. 1946;166:189 97.

    2. Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol. 1967;13:269 88.

    3. Pan BT, Johnstone RM. Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell. 1983;33:967 78.

    4. Harding C, Heuser J, Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J Cell Biol. 1983;97:329 39.

    5. Benz EW Jr., Moses HL. Small, virus-like particles detected in bovine sera by electron microscopy. J Natl Cancer Inst. 1974; 52:1931 4.

    6. Ronquist G, Brody I, Gottfries A, Stegmayr B. An Mg2 and Ca2 -stimulated adenosine triphosphatase in human prostatic fluid: part I. Andrologia. 1978;10:261 72.

    7. Ronquist G, Brody I, Gottfries A, Stegmayr B. An Mg2 and Ca2 -stimulated adenosine triphosphatase in human prostatic fluid: part II. Andrologia. 1978;10:427 33.

    8. Johnstone RM, Adam M, Hammond JR, Orr L, Turbide C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem. 1987;262:9412 20.

    9. La¨sser C. Exosomal RNA as biomarkers and the therapeutic potential of exosome vectors. Expert Opin Biol Ther. 2012; 12(Suppl 1):S189 97.

    10. Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles. 2014;3:24641, doi:

  • Metrics
    No metrics available
Share - Bookmark