Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties

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Sigurdsson, Valgardur; Hilmarsdottir, Bylgja; Sigmundsdottir, Hekla; Fridriksdottir, Agla J. R.; Ringnér, Markus; Villadsen, Rene; Borg, Ake; Agnarsson, Bjarni A.; Petersen, Ole William; Magnusson, Magnus K.; Gudjonsson, Thorarinn;
(2011)
  • Publisher: Public Library of Science
  • Journal: volume 6,issue 9issn: 1932-6203, eissn: 1932-6203
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0023833, pmc: PMC3167828
  • Subject: Cell Differentiation | Endothelial Cells | Research Article | Molecular Cell Biology | Cancer och onkologi | Oncology | Morphogenesis | Metastasis | Cancers and Neoplasms | Stem Cells | Cellular Types | Breast Tumors | Stem Cell Niche | Biology | Developmental Biology | Epithelial Cells | Medicine | Basic Cancer Research | Anatomy and Physiology | Cancer and Oncology | Adult Stem Cells | Q | R | Science | Stem Cell Lines

Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype. Given the close interaction between the vascular endothelium and cancer cells, especially at the invasive fron... View more
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