Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene from Bacillus subtilis: synthesis, characterization, and in vitro melanogenesis inhibition activity in BL6B16 cells

Article English OPEN
Wang, Dan-Dan; Jin, Yan; Wang, Chao; Kim, Yeon-Ju; Perez, Zuly Elizabeth Jimenez; Baek, Nam In; Mathiyalagan, Ramya; Markus, Josua; Yang, Deok-Chun;
  • Publisher: Elsevier BV
  • Journal: Journal of Ginseng Research,volume 42,issue 1,pages42-49 (issn: 1226-8453, eissn: 2093-4947)
  • Related identifiers: doi: 10.1016/j.jgr.2016.12.009, pmc: PMC5766694
  • Subject: Research Article | B16BL6 cell line | melanogenesis | ginsenoside Ia | UDP-glycosyltransferase | ginsenoside F1

Background Ginsenoside F1 has been described to possess skin-whitening effects on humans. We aimed to synthesize a new ginsenoside derivative from F1 and investigate its cytotoxicity and melanogenesis inhibitory activity in B16BL6 cells using recombinant glycosyltransfe... View more
Share - Bookmark