Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene from Bacillus subtilis: synthesis, characterization, and in vitro melanogenesis inhibition activity in BL6B16 cells
Perez, Zuly Elizabeth Jimenez
Baek, Nam In
- Publisher: Elsevier
Journal of Ginseng Research,
(issn: 1226-8453, eissn: 2093-4947)
B16BL6 cell line | Research Article | melanogenesis | Botany | ginsenoside Ia | QK1-989 | UDP-glycosyltransferase | ginsenoside F1
Background: Ginsenoside F1 has been described to possess skin-whitening effects on humans. We aimed to synthesize a new ginsenoside derivative from F1 and investigate its cytotoxicity and melanogenesis inhibitory activity in B16BL6 cells using recombinant glycosyltransf...