A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling

Article English OPEN
Monaghan, Michael ; Browne, Shane ; Schenke-Layland, Katja ; Pandit, Abhay (2014)
  • Publisher: Nature Publishing Group
  • Journal: Molecular Therapy, volume 22, issue 4, pages 786-796 (issn: 1525-0016, eissn: 1525-0024)
  • Related identifiers: doi: 10.1038/mt.2013.288, pmc: PMC3983959
  • Subject: Molecular Biology | Original Article | Genetics | Drug Discovery | Pharmacology | Molecular Medicine

Directing appropriate extracellular matrix remodeling is a key aim of regenerative medicine strategies. Thus, antifibrotic interfering RNA (RNAi) therapy with exogenous microRNA (miR)-29B was proposed as a method to modulate extracellular matrix remodeling following cut... View more
Share - Bookmark