Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

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Seiji Hayashizaki; Shinobu Hirai; Yumi Ito; Yoshiko Honda; Yosefu Arime; Ichiro Sora; Haruo Okado; Tohru Kodama; Masahiko Takada;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 8,issue 10 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3796526, doi: 10.1371/journal.pone.0075975
  • Subject: Q | R | Research Article | Science | Medicine

Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals. The functional relevance of D5 dopamine receptors in the central nervous s... View more
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