Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS Gene

Article English OPEN
Zhang, Qunfeng; Du, Yiqiao; Zhang, Xinju; Kang, Zhihua; Guan, Ming; Wu, Zhiyuan;

Background. KRAS genotyping in tumor samples is a decisive clinical test for the anti-EGFR therapy management. However, the complexity of KRAS mutation landscape across different cancer types and the mosaic effect caused by cancer cellularity and heterogeneity make the ... View more
Share - Bookmark