A novel sweet potato potyvirus open reading frame (ORF) is expressed via polymerase slippage and suppresses RNA silencing

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Untiveros, Milton; Olspert, Allan; Artola, Katrin; Firth, Andrew; Kreuze, Jan F; Valkonen, Jari PT;
  • Publisher: Molecular Plant Pathology
  • Journal: volume 17,issue 7,pages1,111-1,123issn: 1464-6722, eissn: 1364-3703
  • Related identifiers: pmc: PMC4979677, doi: 10.1111/mpp.12366
  • Subject: RNA virus | frameshift | FEATHERY MOTTLE VIRUS | CHLOROTIC-STUNT-VIRUS | RNA silencing suppression | DISTINCT SUPPRESSORS | PROTEIN DOMAINS | COMPLETE NUCLEOTIDE-SEQUENCE | 1183 Plant biology, microbiology, virology | Original Article | VIRAL SUPPRESSOR | STRUCTURE PREDICTION | Original Articles | overlapping gene | transcriptional slippage | HC-PRO | FAMILY POTYVIRIDAE | ARGONAUTE-BINDING | gene expression

The single-stranded, positive-sense RNA genome of viruses in the genus Potyvirus encodes a large polyprotein that is cleaved to yield 10 mature proteins. The first three cleavage products are P1, HCpro and P3. An additional short open reading frame (ORF), called pipo, o... View more