2D QSAR studies of the inhibitory activity of a series of substituted purine derivatives against c-Src tyrosine kinase

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Mukesh C. Sharma;

A series of 34 substituted purine analogues derivatives were subjected to quantitative structure-activity relationship analyses as inhibitors of c-Src tyrosine kinase. Partial least squares regression was applied to derive QSAR models, which were further validated for s... View more
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