publication . Article . Other literature type . 2018

Comparison of Standardized Uptake Value Ratio Calculations in Amyloid Positron Emission Tomography Brain Imaging.

Karin Knesaurek; Geoffrey Warnock; Lale Kostakoglu; Cyrill Burger; null for Alzheimer′s Disease;
Open Access English
  • Published: 01 Jan 2018 Journal: World Journal of Nuclear Medicine, volume 17, issue 1, pages 21-26 (issn: 1450-1147, eissn: 1607-3312, Copyright policy)
  • Publisher: Medknow Publications & Media Pvt Ltd
  • Country: Switzerland
Abstract
Amyloid positron emission tomography (PET) imaging with florbetapir 18F (18F-AV-45) allows in vivo assessment of cerebral amyloid load and can be used in the evaluation of progression of Alzheimer's disease (AD) and other dementias associated with b-amyloid. However, cortical amyloid deposition can occur in healthy cases, as well as in patients with AD and quantification of cortical amyloid burden can improve the 18F-AV-45 PET imaging evaluations. The quantification is mostly performed by cortical-to-cerebellum standardized uptake value ratio (SUVr). The aim of our study was to compare two methods for SUVr calculations in amyloid florbetapir 18F PET brain imagin...
Subjects
free text keywords: Clinic for Nuclear Medicine, 610 Medicine & health, Original Article, Alzheimer's disease, florbetapir, positron emission tomography amyloid imaging, Medical physics. Medical radiology. Nuclear medicine, R895-920, Brain segmentation, Medicine, business.industry, business, Standardized uptake value, Repeatability, Florbetapir (18F), chemistry.chemical_compound, chemistry, Rank correlation, Nuclear medicine, Positron emission tomography, medicine.diagnostic_test, Magnetic resonance imaging, Neuroimaging
Funded by
NIH| Alzheimers Disease Neuroimaging Initiative
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 1U01AG024904-01
  • Funding stream: NATIONAL INSTITUTE ON AGING
,
CIHR
Project
  • Funder: Canadian Institutes of Health Research (CIHR)
,
WT
Project
  • Funder: Wellcome Trust (WT)
Communities
Neuroinformatics

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publication . Article . Other literature type . 2018

Comparison of Standardized Uptake Value Ratio Calculations in Amyloid Positron Emission Tomography Brain Imaging.

Karin Knesaurek; Geoffrey Warnock; Lale Kostakoglu; Cyrill Burger; null for Alzheimer′s Disease;