publication . Preprint . 2016

IMPORT AND EXPORT OF GOLD NANOPARTICLES: EXCHANGE RATE IN CANCER CELLS AND FIBROBLASTS

Vladimir Ivošev; Gloria Jiménez Sánchez; Darine Abi Haidar; Rana Bazzi; Stéphane Roux; Sandrine Lacombe;
Open Access English
  • Published: 08 Dec 2016
  • Publisher: Cold Spring Harbor Laboratory
Abstract
<jats:title>Abstract</jats:title><jats:p>Cancer is one of the leading causes of death. Radiation therapy is an important modality used in cancer treatment being highly cost-effective. Major flaw of radiotherapy is lack of selectivity between cancerous and healthy tissues. Amelioration of radiotherapy by using high-Z nanoparticles as radiation enhancers is one of potential solutions. Gold nanoparticles (AuNPs) are commonly used as radioenhancers. Understanding the interaction between cancer cells and AuNPs is essential in order to achieve best possible radioenhancing effects, while sparing healthy tissues. This work aims to elucidate interactions of ultrasmall (c...
Subjects
free text keywords: Colloidal gold, Biophysics, Cancer cell, Bioinformatics, Cancer, medicine.disease, medicine, Biology, Internalization, media_common.quotation_subject, media_common, Radiation therapy, medicine.medical_treatment, In vitro, Cell, medicine.anatomical_structure, Nanoparticle
Funded by
EC| ARGENT
Project
ARGENT
Advanced Radiotherapy, Generated by Exploiting Nanoprocesses and Technologies
  • Funder: European Commission (EC)
  • Project Code: 608163
  • Funding stream: FP7 | SP3 | PEOPLE
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