publication . Article . 2017

Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders

Lijun Zhang; Xiaofang Jia; Jun-O Jin; Hongzhou Lu; Zhimi Tan;
Open Access English
  • Published: 01 Apr 2017 Journal: Genomics, Proteomics & Bioinformatics, volume 15, issue 2, pages 110-120 (issn: 1672-0229, eissn: 2210-3244, Copyright policy)
  • Publisher: Elsevier
Abstract
Human immunodeficiency virus-1 (HIV-1) mainly relies on host factors to complete its life cycle. Hence, it is very important to identify HIV-regulated host proteins. Proteomics is an excellent technique for this purpose because of its high throughput and sensitivity. In this review, we summarized current technological advances in proteomics, including general isobaric tags for relative and absolute quantitation (iTRAQ) and stable isotope labeling by amino acids in cell culture (SILAC), as well as subcellular proteomics and investigation of posttranslational modifications. Furthermore, we reviewed the applications of proteomics in the discovery of HIV-related dis...
Subjects
free text keywords: HIV-1, Proteomics, Review, Interaction, iTRAQ, SILAC, Biology (General), QH301-705.5
103 references, page 1 of 7

Suguimoto, S.P., Techasrivichien, T., Musumari, P.M., El-saaidi, C., Lukhele, B.W., Ono-Kihara, M.. Changing patterns of HIV epidemic in 30 years in East Asia. Curr HIV/AIDS Rep. 2014; 11: 134-145 [PubMed]

Bruun, J.N., Skeie, L., Maeland, A., Dudman, S.G., Sannes, M., Ormaasen, V.. HIV/AIDS–from lethal syndrome to chronic disease. Tidsskr Nor Laegeforen. 2006; 126: 3121-3124 [PubMed]

Kumari, G., Singh, R.K.. Anti-HIV drug development: structural features and limitations of present day drugs and future challenges in the successful HIV/AIDS treatment. Curr Pharm Des. 2013; 19: 1767-1783 [PubMed]

Este, J.A., Cihlar, T.. Current status and challenges of antiretroviral research and therapy. Antiviral Res. 2010; 85: 25-33 [PubMed]

Clavel, F., Hance, A.J.. HIV drug resistance. N Engl J Med. 2004; 350: 1023-1035 [PubMed]

Kimata, J.T., Rice, A.P., Wang, J.. Challenges and strategies for the eradication of the HIV reservoir. Curr Opin Immunol. 2016; 42: 65-70 [OpenAIRE] [PubMed]

Frankel, A.D., Young, J.A.. HIV-1: fifteen proteins and an RNA. Annu Rev Biochem. 1998; 67: 1-25 [PubMed]

Friedrich, B.M., Dziuba, N., Li, G., Endsley, M.A., Murray, J.L., Ferguson, M.R.. Host factors mediating HIV-1 replication. Virus Res. 2011; 161: 101-114 [PubMed]

Li, M.. Proteomics in the investigation of HIV-1 interactions with host proteins. Proteomics Clin Appl. 2015; 9: 221-234 [OpenAIRE] [PubMed]

Sattentau, Q.J., Weiss, R.A.. The CD4 antigen: physiological ligand and HIV receptor. Cell. 1988; 52: 631-633 [PubMed]

Moore, J.P., Kitchen, S.G., Pugach, P., Zack, J.A.. The CCR5 and CXCR4 coreceptors–central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses. 2004; 20: 111-126 [PubMed]

Brass, A.L., Dykxhoorn, D.M., Benita, Y., Yan, N., Engelman, A., Xavier, R.J.. Identification of host proteins required for HIV infection through a functional genomic screen. Science. 2008; 319: 921-926 [PubMed]

Llano, M., Saenz, D.T., Meehan, A., Wongthida, P., Peretz, M., Walker, W.H.. An essential role for LEDGF/p75 in HIV integration. Science. 2006; 314: 461-464 [PubMed]

Wei, P., Garber, M.E., Fang, S.M., Fischer, W.H., Jones, K.A.. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell. 1998; 92: 451-462 [PubMed]

Garrus, J.E., von Schwedler, U.K., Pornillos, O.W., Morham, S.G., Zavitz, K.H., Wang, H.E.. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 2001; 107: 55-65 [OpenAIRE] [PubMed]

103 references, page 1 of 7
Abstract
Human immunodeficiency virus-1 (HIV-1) mainly relies on host factors to complete its life cycle. Hence, it is very important to identify HIV-regulated host proteins. Proteomics is an excellent technique for this purpose because of its high throughput and sensitivity. In this review, we summarized current technological advances in proteomics, including general isobaric tags for relative and absolute quantitation (iTRAQ) and stable isotope labeling by amino acids in cell culture (SILAC), as well as subcellular proteomics and investigation of posttranslational modifications. Furthermore, we reviewed the applications of proteomics in the discovery of HIV-related dis...
Subjects
free text keywords: HIV-1, Proteomics, Review, Interaction, iTRAQ, SILAC, Biology (General), QH301-705.5
103 references, page 1 of 7

Suguimoto, S.P., Techasrivichien, T., Musumari, P.M., El-saaidi, C., Lukhele, B.W., Ono-Kihara, M.. Changing patterns of HIV epidemic in 30 years in East Asia. Curr HIV/AIDS Rep. 2014; 11: 134-145 [PubMed]

Bruun, J.N., Skeie, L., Maeland, A., Dudman, S.G., Sannes, M., Ormaasen, V.. HIV/AIDS–from lethal syndrome to chronic disease. Tidsskr Nor Laegeforen. 2006; 126: 3121-3124 [PubMed]

Kumari, G., Singh, R.K.. Anti-HIV drug development: structural features and limitations of present day drugs and future challenges in the successful HIV/AIDS treatment. Curr Pharm Des. 2013; 19: 1767-1783 [PubMed]

Este, J.A., Cihlar, T.. Current status and challenges of antiretroviral research and therapy. Antiviral Res. 2010; 85: 25-33 [PubMed]

Clavel, F., Hance, A.J.. HIV drug resistance. N Engl J Med. 2004; 350: 1023-1035 [PubMed]

Kimata, J.T., Rice, A.P., Wang, J.. Challenges and strategies for the eradication of the HIV reservoir. Curr Opin Immunol. 2016; 42: 65-70 [OpenAIRE] [PubMed]

Frankel, A.D., Young, J.A.. HIV-1: fifteen proteins and an RNA. Annu Rev Biochem. 1998; 67: 1-25 [PubMed]

Friedrich, B.M., Dziuba, N., Li, G., Endsley, M.A., Murray, J.L., Ferguson, M.R.. Host factors mediating HIV-1 replication. Virus Res. 2011; 161: 101-114 [PubMed]

Li, M.. Proteomics in the investigation of HIV-1 interactions with host proteins. Proteomics Clin Appl. 2015; 9: 221-234 [OpenAIRE] [PubMed]

Sattentau, Q.J., Weiss, R.A.. The CD4 antigen: physiological ligand and HIV receptor. Cell. 1988; 52: 631-633 [PubMed]

Moore, J.P., Kitchen, S.G., Pugach, P., Zack, J.A.. The CCR5 and CXCR4 coreceptors–central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses. 2004; 20: 111-126 [PubMed]

Brass, A.L., Dykxhoorn, D.M., Benita, Y., Yan, N., Engelman, A., Xavier, R.J.. Identification of host proteins required for HIV infection through a functional genomic screen. Science. 2008; 319: 921-926 [PubMed]

Llano, M., Saenz, D.T., Meehan, A., Wongthida, P., Peretz, M., Walker, W.H.. An essential role for LEDGF/p75 in HIV integration. Science. 2006; 314: 461-464 [PubMed]

Wei, P., Garber, M.E., Fang, S.M., Fischer, W.H., Jones, K.A.. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell. 1998; 92: 451-462 [PubMed]

Garrus, J.E., von Schwedler, U.K., Pornillos, O.W., Morham, S.G., Zavitz, K.H., Wang, H.E.. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 2001; 107: 55-65 [OpenAIRE] [PubMed]

103 references, page 1 of 7
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publication . Article . 2017

Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders

Lijun Zhang; Xiaofang Jia; Jun-O Jin; Hongzhou Lu; Zhimi Tan;