Genome-wide association study of retinopathy in individuals without diabetes.

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Richard A Jensen ; Xueling Sim ; Xiaohui Li ; Mary Frances Cotch ; M Kamran Ikram ; Elizabeth G Holliday ; Gudny Eiriksdottir ; Tamara B Harris ; Fridbert Jonasson ; Barbara E K Klein ; Lenore J Launer ; Albert Vernon Smith ; Eric Boerwinkle ; Ning Cheung ; Alex W Hewitt ; Gerald Liew ; Paul Mitchell ; Jie Jin Wang ; John Attia ; Rodney Scott ; Nicole L Glazer ; Thomas Lumley ; Barbara McKnight ; Bruce M Psaty ; Kent Taylor ; Albert Hofman ; Paulus T V M de Jong ; Fernando Rivadeneira ; Andre G Uitterlinden ; Wan-Ting Tay ... view all 49 authors
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 8, issue 2 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0054232, pmc: PMC3564946
  • Subject: human genetics | Research Article | biology | Medicine | genetic epidemiology | biomarker epidemiology | epidemiology | Q | R | genetics | clinical epidemiology | Science | ophthalmology | retinal disorders | genome-wide association studies

Background: Mild retinopathy (microaneurysms or dot-blot hemorrhages) is observed in persons without diabetes or hypertension and may reflect microvascular disease in other organs. We conducted a genome-wide association study (GWAS) of mild retinopathy in persons withou... View more