The Favorable Effect of Mesenchymal Stem Cell Treatment on the Antioxidant Protective Mechanism in the Corneal Epithelium and Renewal of Corneal Optical Properties Changed after Alkali Burns

Article English OPEN
Cejka, Cestmir; Holan, Vladimir; Trosan, Peter; Zajicova, Alena; Javorkova, Eliska; Cejkova, Jitka;
(2016)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Oxidative Medicine and Cellular Longevity,volume 2,016 (issn: 1942-0900, eissn: 1942-0994)
  • Related identifiers: pmc: PMC4736412, doi: 10.1155/2016/5843809
  • Subject: Cytology | Research Article | QH573-671 | Article Subject
    mesheuropmc: eye diseases | sense organs

The aim of this study was to examine whether mesenchymal stem cells (MSCs) and/or corneal limbal epithelial stem cells (LSCs) influence restoration of an antioxidant protective mechanism in the corneal epithelium and renewal of corneal optical properties changed after a... View more
  • References (30)
    30 references, page 1 of 3

    Kubota, M., Shimmura, S., Kubota, S., Miyashita, H., Kato, N., Noda, K., Ozawa, Y., Usui, T., Ishida, S., Umezawa, K., Kurihara, T., Tsubota, K.. Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. Investigative Ophthalmology and Visual Science. 2011; 52 (1): 427-433

    Cejkova, J., Trosan, P., Cejka, C., Lencova, A., Zajicova, A., Javorkova, E., Kubinova, S., Sykova, E., Holan, V.. Suppression of alkali-induced oxidative injury in the cornea by mesenchymal stem cells growing on nanofiber scaffolds and transferred onto the damaged corneal surface. Experimental Eye Research. 2013; 116 (5): 312-323

    Cejkova, J., Stipek, S., Crkovska, J., Ardan, T.. Changes of superoxide dismutase, catalase and glutathione peroxidase in the corneal epithelium after UVB rays. Histochemical and biochemical study. Histology and Histopathology. 2000; 15 (4): 1043-1050

    Čejková, J., Štípek, S., Crkovská, J., Ardan, T., Midelfart, A.. Reactive oxygen species (ROS)-generating oxidases in the normal rabbit cornea and their involvement in the corneal damage evoked by UVB rays. Histology and Histopathology. 2001; 16 (2): 523-533

    Finkel, T., Holbrook, N. J.. Oxidants, oxidative stress and the biology of ageing. Nature. 2000; 408 (6809): 239-247

    Čejková, J., Ardan, T., Čejka, Č., Kovačeva, J., Zídek, Z.. Irradiation of the rabbit cornea with UVB rays stimulates the expression of nitric oxide synthases-generated nitric oxide and the formation of cytotoxic nitrogen-related oxidants. Histology and Histopathology. 2005; 20 (2): 467-473

    Arnal, E., Peris-Martínez, C., Menezo, J. L., Johnsen-Soriano, S., Romero, F. J.. Oxidative stress in keratoconus?. Investigative Ophthalmology & Visual Science. 2011; 52 (12): 8592-8597

    Buddi, R., Lin, B., Atilano, S. R., Zorapapel, N. C., Kenney, M. C., Brown, D. J.. Evidence of oxidative stress in human corneal diseases. Journal of Histochemistry and Cytochemistry. 2002; 50 (3): 341-351

    Zhou, L., Sawaguchi, S., Twining, S. S., Sugar, J., Feder, R. S., Yue, B. Y. J. T.. Expression of degradative enzymes and protease inhibitors in corneas with keratoconus. Investigative Ophthalmology and Visual Science. 1998; 39 (7): 1117-1124

    Valle-Prieto, A., Conget, P. A.. Human mesenchymal stem cells efficiently manage oxidative stress. Stem Cells and Development. 2010; 19 (12): 1885-1893

  • Metrics
    No metrics available
Share - Bookmark