publication . Article . 2013

Dopamine Signaling in reward-related behaviors

Ja-Hyun eBaik;
Open Access English
  • Published: 01 Oct 2013 Journal: Frontiers in Neural Circuits, volume 7 (issn: 1662-5110, eissn: 1662-5110, Copyright policy)
  • Publisher: Frontiers Media S.A.
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic dopaminergic pathway. Changes in DA mesolimbic neurotransmission have been found to modify behavioral responses to various environmental stimuli associated with reward behaviors. Psychostimulants, drugs of abuse, and natural reward such as food can cause substantial synaptic modifications to the mesolimbic DA system. Recent studies using optogenetics and DREADDs, together with neuron-specific or circuit-specific genetic manipulations have improved our understanding of DA signaling in the reward circuit, and provided a means to identify the neural substrates of complex behaviors su...
free text keywords: Review Article, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neuroscience, drug addiction, reward circuit, dopamine, dopamine receptor, food reward
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publication . Article . 2013

Dopamine Signaling in reward-related behaviors

Ja-Hyun eBaik;