Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria

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Nguetse, Christian N. ; Adegnika, Ayola Akim ; Agbenyega, Tsiri ; Ogutu, Bernhards R. ; Krishna, Sanjeev ; Kremsner, Peter G. ; Velavan, Thirumalaisamy P. (2017)
  • Publisher: BioMed Central
  • Journal: Malaria Journal, volume 16 (issn: 1475-2875, eissn: 1475-2875)
  • Related identifiers: doi: 10.1186/s12936-017-1868-y, pmc: PMC5442681
  • Subject: Africa | Pfmdr1 | Pfatp6 | Malaria | Pfk13 | Research | Resistance | RC955-962 | RC109-216 | P. falciparum | Infectious and parasitic diseases | Anti-malarial drugs | Arctic medicine. Tropical medicine
    mesheuropmc: parasitic diseases

Abstract Background The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca2+-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Their frequency distributions were deter... View more
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