A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts

Article English OPEN
Suh, Eric J ; Remillard, Matthew Y ; Legesse-Miller, Aster ; Johnson, Elizabeth L ; Lemons, Johanna MS ; Chapman, Talia R ; Forman, Joshua J ; Kojima, Mina ; Silberman, Eric S ; Coller, Hilary A (2012)
  • Publisher: Springer Nature
  • Journal: Genome Biology, volume 13, issue 12, pages R121-R121 (issn: 1465-6906, eissn: 1465-6914)
  • Related identifiers: doi: 10.1186/gb-2012-13-12-r121, pmc: PMC3924601
  • Subject: Microarray | miR-29 | Fibroblast | Proliferation | Cell cycle | MicroRNA | Quiescence | Research | Extracellular matrix

Background Although quiescence (reversible cell cycle arrest) is a key part in the life history and fate of many mammalian cell types, the mechanisms of gene regulation in quiescent cells are poorly understood. We sought to clarify the role of microRNAs as regulators of... View more