Increased bcl-2 Protein Levels in Rat Primary Astrocyte Culture Following Chronic Lithium Treatment

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Mojtaba Keshavarz; Masoumeh Emamghoreishi; Ali Akbar Nekooeian; Jerry J. Warsh; Hamid Reza Zare;
(2013)
  • Publisher: Shiraz University of Medical Sciences
  • Journal: Iranian Journal of Medical Sciences,volume 38,issue 3,pages255-262 (issn: 0253-0716, eissn: 1735-3688)
  • Related identifiers: pmc: PMC3808950
  • Subject: Original Article | Lithium | Primary cell culture | bcl-2 | R5-920 | Medicine (General) | Neuron | Astrocytes

Background: B cell CLL/lymphoma 2 protein, bcl-2, is an important anti-apoptotic factor that has been implicated in lithium’s neuroprotective effect. However, most studies have focused on assessing the effects of lithium in neurons, ignoring examination of bcl-2 in astr... View more
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