Macrolactone Nuiapolide, Isolated from a Hawaiian Marine Cyanobacterium, Exhibits Anti-Chemotactic Activity
Article, Other literature type
- Publisher: Multidisciplinary Digital Publishing Institute
(issn: 1660-3397, eissn: 1660-3397)
cell cycle | polyketide | cyanobacteria | macrolactone | Article | Biology (General) | chemotaxis | QH301-705.5
A new bioactive macrolactone, nuiapolide (1) was identified from a marine cyanobacterium collected off the coast of Niihau, near Lehua Rock. The natural product exhibits anti-chemotactic activity at concentrations as low as 1.3 μM against Jurkat cells, cancerous T lymph...