DNA vaccine expressing herpes simplex virus 1 glycoprotein C and D protects mice against herpes simplex keratitis

Article, Other literature type English OPEN
Li-Li Dong ; Ru Tang ; Yu-Jia Zhai ; Tejsu Malla ; Kai Hu (2017)
  • Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
  • Journal: International Journal of Ophthalmology (issn: 2222-3959, eissn: 2227-4898)
  • Related identifiers: pmc: PMC5686359, doi: 10.18240/ijo.2017.11.01
  • Subject: keratitis | RE1-994 | immune response | herpes simplex virus 1 | nanocarrier | Ophthalmology | gC-based DNA vaccine | Basic Research | 1639

AIM: To investigate whether DNA vaccine encoding herpes simplex virus 1 (HSV-1) glycoprotein C (gC) and glycoprotein D (gD) will achieve better protective effect against herpes simplex keratitis (HSK) than DNA vaccine encoding gD alone. METHODS: DNA vaccine expressin... View more
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