Does adaptation to vertebrate codon usage relate to flavivirus emergence potential?

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Di Paola, Nicholas; Freire, Caio César de Melo; Zanotto, Paolo Marinho de Andrade;
(2018)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 13,issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0191652, pmc: PMC5792106
  • Subject: Microbial Pathogens | Research Article | Eukaryota | Infectious Diseases | Pathology and Laboratory Medicine | Geographical Locations | West Nile virus | Pathogens | People and Places | Species Interactions | Plant Science | Flaviviruses | Tobamoviruses | Animals | Viral Transmission and Infection | Europe | Plant Pathology | Disease Vectors | Mosquitoes | Viruses | Biology and Life Sciences | Insect Vectors | Dengue Virus | Microbiology | Arthropoda | Plant Viral Pathogens | Medicine | Plant Pathogens | Insects | Viral Vectors | Vertebrates | Q | Medical Microbiology | Viral Pathogens | R | RNA viruses | Tobacco Mosaic Virus | Virology | Science | Organisms | Medicine and Health Sciences | Invertebrates
    mesheuropmc: sense organs

Codon adaptation index (CAI) is a measure of synonymous codon usage biases given a usage reference. Through mutation, selection, and drift, viruses can optimize their replication efficiency and produce more offspring, which could increase the chance of secondary transmi... View more
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