Negative Effects of High Glucose Exposure in Human Gonadotropin-Releasing Hormone Neurons

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Annamaria Morelli; Paolo Comeglio; Erica Sarchielli; Ilaria Cellai; Linda Vignozzi; Gabriella B. Vannelli; Mario Maggi; (2013)
  • Publisher: Hindawi Limited
  • Journal: International Journal of Endocrinology,volume 2,013 (issn: 1687-8337, eissn: 1687-8345)
  • Related identifiers: pmc: PMC3893744, doi: 10.1155/2013/684659
  • Subject: Research Article | RC648-665 | Diseases of the endocrine glands. Clinical endocrinology | Neuroni GnRH-secernenti; glucose | Article Subject
    mesheuropmc: endocrine system | hormones, hormone substitutes, and hormone antagonists

Metabolic disorders are often associated with male hypogonadotropic hypogonadism, suggesting that hypothalamic defects involving GnRH neurons may impair the reproductive function. Among metabolic factors hyperglycemia has been implicated in the control of the reproducti... View more
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