Assessment of antibody-dependent respiratory burst activity from mouse neutrophils on Plasmodium yoelii malaria challenge outcome

Article English OPEN
Llewellyn, David; de Cassan, Simone C.; Williams, Andrew R.; Douglas, Alexander D.; Forbes, Emily K.; Adame-Gallegos, Jaime R.; Shi, Jianguo; Pleass, Richard J.; Draper, Simon J.;
  • Publisher: Society for Leukocyte Biology
  • Journal: Journal of Leukocyte Biology,volume 95,issue 2,pages369-382 (issn: 0741-5400, eissn: 1938-3673)
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  • Related identifiers: pmc: PMC3896657, doi: 10.1189/jlb.0513274
  • Subject: qx_135 | merozoite | Host Defense & Pathophysiology | qw_806 | malaria | neutrophil | wc_750 | vaccine | wh_200 | MSP1 | assay | qw_575 | ROS | Fc receptor
    mesheuropmc: parasitic diseases

New tools are required to expedite the development of an effective vaccine against the blood-stage infection with the human malaria parasite Plasmodium falciparum. This work describes the assessment of the ADRB assay in a mouse model, characterizing the functional inter... View more