Resveratrol Inhibits the Invasion of Glioblastoma-Initiating Cells via Down-Regulation of the PI3K/Akt/NF-κB Signaling Pathway

Other literature type, Article English OPEN
Jiao, Yuming; Li, Hao; Liu, Yaodong; Guo, Anchen; Xu, Xiaoxue; Qu, Xianjun; Wang, Shuo; Zhao, Jizong; Li, Ye; Cao, Yong;
  • Publisher: MDPI
  • Journal: Nutrients,volume 7,issue 6,pages4,383-4,402 (issn: 2072-6643, eissn: 2072-6643)
  • Related identifiers: pmc: PMC4488790, doi: 10.3390/nu7064383
  • Subject: NF-κB | Nutrition. Foods and food supply | RES | glioblastoma-initiating cells | TX341-641 | invasion | MMP-2 | Article | PI3K/Akt

Invasion and metastasis of glioblastoma-initiating cells (GICs) are thought to be responsible for the progression and recurrence of glioblastoma multiforme (GBM). A safe drug that can be applied during the rest period of temozolomide (TMZ) maintenance cycles would grea... View more
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