Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation

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Kwan, Kelvin Y.; Corey, David P.;

Soon after its discovery ten years ago, the ion channel TRPA1 was proposed as a sensor of noxious cold. Evidence for its activation by painfully cold temperatures (below ~15° C) has been mixed, however. Some groups found that cold elicits a nonselective conductance in c... View more
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