Differential Motor Neuron Impairment and Axonal Regeneration in Sporadic and Familiar Amyotrophic Lateral Sclerosis with SOD-1 Mutations: Lessons from Neurophysiology
Other literature type, Article
- Publisher: Molecular Diversity Preservation International (MDPI)
International Journal of Molecular Sciences,
(issn: 1422-0067, eissn: 1422-0067)
Chemistry | macro-EMG | QD1-999 | SOD-1 carriers | MUNE | Amyotrophic Lateral Sclerosis | Biology (General) | Article | QH301-705.5
Amyotrophic Lateral Sclerosis (ALS) is a degenerative disorder of the motor system. About 10% of cases are familial and 20% of these families have point mutations in the Cu/Zn superoxide dismutase 1 (SOD-1) gene. SOD-1 catalyses the superoxide radical (O−2) into hydroge...