Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
Elshikha, Ahmed S.
Mahdi, Mahmoud A.
- Publisher: Public Library of Science
(issn: 1932-6203, eissn: 1932-6203)
Mouse Models | Immune System Proteins | Animal Models | Cell Differentiation | Research Article | Diagnostic Medicine | Lupus Erythematosus | Signs and Symptoms | Proteinuria | Rheumatology | Pathology and Laboratory Medicine | Immunoassays | Clinical Medicine | Systemic Lupus Erythematosus | Molecular Development | Proteins | Immune System | Enzyme-Linked Immunoassays | Cytokines | Antibodies | Immunology | Autoantibodies | Autoimmune Diseases | Biology and Life Sciences | Immune Physiology | Developmental Biology | Research and Analysis Methods | Physiology | Medicine | Immunologic Techniques | Innate Immune System | Q | R | Secretion | Model Organisms | Clinical Immunology | Science | Biochemistry | Medicine and Health Sciences | Physiological Processes
mesheuropmc: skin and connective tissue diseases | immune system diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder with a worldwide distribution and considerable mortality and morbidity. Although the pathogenesis of this disease remains elusive, over-reactive dendritic cells (DCs) play a critical role in the disease develo...