Tamoxifen decreases lithium-induced natriuresis in rats with nephrogenic diabetes insipidus

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Stine Julie Tingskov; Tae-Hwan Kwon; Jørgen Frøkiær; Rikke Nørregaard;

<p>Lithium is widely used in the treatment of bipolar affective disorders, but often causes nephrogenic diabetes insipidus (NDI), a condition characterized by a severe urinary concentrating defect. Lithium-induced NDI is associated with dysregulation of the amiloride-se... View more
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