Mechanical stress activates NMDA receptors in the absence of agonists

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Mohammad Mehdi Maneshi; Bruce Maki; Radhakrishnan Gnanasambandam; Sophie Belin; Gabriela K. Popescu; Frederick Sachs; Susan Z. Hua;

While studying the physiological response of primary rat astrocytes to fluid shear stress in a model of traumatic brain injury (TBI), we found that shear stress induced Ca2+ entry. The influx was inhibited by MK-801, a specific pore blocker of N-Methyl-D-aspartic acid r... View more
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