Adult-onset hypothyroidism enhances fear memory and upregulates mineralocorticoid and glucocorticoid receptors in the amygdala.

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Ana Montero-Pedrazuela; Iván Fernández-Lamo; María Alieva; Inmaculada Pereda-Pérez; César Venero; Ana Guadaño-Ferraz;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 6,issue 10 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0026582, pmc: PMC3200331
  • Subject: Endocrine System | Neuroendocrinology | Animal Models | Research Article | Hypothyroidism | Neurochemistry | Endocrine Physiology | Neurological System | Biology | Rat | Neuroscience | Medicine | Anatomy and Physiology | Central Nervous System | Cellular Neuroscience | Q | R | Thyroid | Model Organisms | Learning and Memory | Science | Behavioral Neuroscience | Endocrinology
    mesheuropmc: endocrine system diseases | hormones, hormone substitutes, and hormone antagonists

Hypothyroidism is the most common hormonal disease in adults, which is frequently accompanied by learning and memory impairments and emotional disorders. However, the deleterious effects of thyroid hormones deficiency on emotional memory are poorly understood and often ... View more
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