A functional data analysis approach for genetic association studies

Preprint, Other literature type English OPEN
Reimherr, Matthew; Nicolae, Dan;
  • Publisher: The Institute of Mathematical Statistics
  • Journal: issn: 1932-6157
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1214/13-AOAS692
  • Subject: Statistics - Applications | functional linear model | functional analysis of variance | hypothesis testing | Functional data analysis | longitudinal data analysis | genome wide association study

We present a new method based on Functional Data Analysis (FDA) for detecting associations between one or more scalar covariates and a longitudinal response, while correcting for other variables. Our methods exploit the temporal structure of longitudinal data in ways th... View more
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