Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

Article English OPEN
Leung, Yuk Yee ; Toledo, Jon B. ; Nefedov, Alexey ; Polikar, Robi ; Raghavan, Nandini ; Xie, Sharon X. ; Farnum, Michael ; Schultz, Tim ; Baek, Young ; Van Deerlin, Vivianna M. ; Hu, William T. ; Holtzman, David M. ; Fagan, Anne M. ; Perrin, Richard J. ; Grossman, Murray ; Soares, Holly D. ; Kling, Mitchel A. ; Mailman, Matthew ; Arnold, Steven E. ; Narayan, Vaibhav A. ; Lee, Virginia M-Y. ; Shaw, Leslie M. ; Baker, David ; Wittenberg, Gayle M. ; Trojanowski, John Q. ; Wang, Li-San (2015)
  • Publisher: Elsevier
  • Journal: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, volume 1, issue 3, pages 339-348 (issn: 2352-8729, eissn: 2352-8729)
  • Related identifiers: pmc: PMC4672388, doi: 10.1016/j.dadm.2015.06.008
  • Subject: Alzheimer's disease | Biomarkers | Cerebrospinal fluid | Dementia | Cognitive impairment | CSF Biomarkers | Amyloid beta

Introduction The dynamic range of cerebrospinal fluid (CSF) amyloid β (Aβ1–42) measurement does not parallel to cognitive changes in Alzheimer's disease (AD) and cognitively normal (CN) subjects across different studies. Therefore, identifying novel proteins to characte... View more
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